CHLORACETYL CHLORIDE

PRODUCT IDENTIFICATION
CAS NO. 79-04-9

CHLORACETYL CHLORIDE

EINECS NO. 201-171-6
FORMULA ClCH2COCl
MOL WT. 112.94
H.S. CODE 2915.90

TOXICITY

 Oral rat LD50: 208 mg/kg
SYNONYMS Chloroacetyl chloride; Monochloroacetyl chloride;
Chlorid kyseliny chloroctove; Chlorure de Chloracetyle (French);  

SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

Clear to slightly yellow fuming liquid

MELTING POINT -23 C
BOILING POINT

105 C

SPECIFIC GRAVITY 1.415 - 1.42
SOLUBILITY IN WATER Rapidly hydrolysis
pH

 

VAPOR DENSITY  

AUTOIGNITION

 

REFRACTIVE INDEX

 

NFPA RATINGS

 Health: 3 Flammability: 0 Reactivity: 1
FLASH POINT > 100 C
STABILITY Stable under ordinary conditions. but will fume when exposed to atmospheric moisture to form HCl and acetic acid.

DESCRIPTION AND APPLICATIONS
Chloracetyl Chloride is a clear to slightly yellowish liquid with a strong pungent odor similar to that of hydrochloric acid; melting point 23 C; boiling point 105 C. Chloracetyl chloride, a bifunctional chloride, offers following molecules for the end products of agrochemicals, pharmaceuticals, dyes, textile auxiliaries, paper modifiers, plastic additives, and peroxide compounds.
  • Chloroacetanilide
  • Ring closure
  • Chloroacetates
  • Chlorothioacetates
  • Chloroacetic acid
  • Chloroacetamides
  • Olefin saturation
SALES SPECIFICATION

APPEARANCE

Clear liquid

ASSAY

99.0% min

ACETYL CHLORIDE

0.5% max

COLOR

30 max, Hazen

TRANSPORTATION
PACKING 275kgs in drum
HAZARD CLASS 3 (Packing group: I)
UN NO. 1752
OTHER INFORMATION
Hazard Symbols: T C N, Risk Phrases: 14-23/24/25-35-48/23-50, Safety Phrases: 7/8-9-26-36/37/39-45-61

GENERAL DESCRIPTION OF ACYL HALIDE
Acyl is a radical formed from an organic acid by removal of a hydroxyl group. The general formula of acyl compound is RCO-. Acyl halide is one of a large group of organic substances containing the halocarbonyl group, have the general formula RCO·X, where X is a halogen atom (fluorine, chlorine, bromine, iodine, and astatine) and R may be aliphatic, alicyclic, aromatic, and H etc. In substitutive chemical nomenclature, their names are formed by adding '-oyl' as a suffix to the name of the parent compound; ethanoyl chloride, CH3COCl, is an example. The terms acyl and aroyl halides refer to aliphatic or aromatic derivatives, respectively. Acyl halides are made by replacing the -OH group in carboxylic acids by halogen using halogenating agents. They react readily with water, alcohols, and amines and are widely used in organic synthetic process whereby the acyl group is incorporated into the target molecules by substitution of addition-elimination sequence called acylation reaction.  Acylation reaction involves substitution by an electron donor (nucleophile) at the electrophilic carbonyl group (C=O). Common nucleophiles in the acylation reaction are aliphatic and aromatic alcohols, both of which give rise to esters and amines (RNH2) which give amides. The carboxylic acid (X = OH) itself can function as an acylating agent when it is protonated by a strong acid catalyst as in the direct esterification of an alcohol. Two common acylation agents, with the general formula RCOX, are acid halides (X = halogen atom) and anhydrides (X = OCOR). Schotten-Baumann reaction is an acylation reaction that uses an acid chloride in the presence of dilute alkali to acylate the hydroxyl and amino group of organic compounds. There are also other acylating agents. Chloride is used in agrochemicals and pharmaceuticals manufacturing. Acyl halide compounds are used as an intermediate for agrochemicals and pharmaceuticals, dyes, and peroxide compounds as well as textile auxiliaries, emulsifiers.